Target：BMP-3B

Fields：Cytokine-cytokine receptor interaction

Gene Name：GDF10 BMP3B

Protein Name：Bone morphogenetic protein 3B (BMP-3B) (Bone-inducing protein) (BIP) (Growth/differentiation factor 10) (GDF-10)

Human Gene Id：2662

Human Swiss Prot No：P55107

Mouse Swiss Prot No：P97737

Rat Swiss Prot No：P55108

Immunogen：Synthesized peptide derived from part region of human protein AA range: 421-470

Specificity：BMP3B Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：52kD

Background：growth differentiation factor 10(GDF10) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer. [provided by RefSeq, Jul 2016],

Function：similarity:Belongs to the TGF-beta family.,subunit:Homodimer or heterodimer .,tissue specificity:Expressed in femur, brain, lung, skeletal muscle, pancreas and testis.,

Subcellular Location：Secreted .

Expression：Expressed in femur, brain, lung, skeletal muscle, pancreas and testis.