Target：BKRB2

Fields：Calcium signaling pathway;cGMP-PKG signaling pathway;Sphingolipid signaling pathway;Neuroactive ligand-receptor interaction;Complement and coagulation cascades;Inflammatory mediator regulation of TRP channels;Regulation of actin cytoskeleton;Endocrine and other factor-regulated calcium reabsorption;Chagas disease;Pathways in cancer

Gene Name：BDKRB2 BKR2

Protein Name：B2 bradykinin receptor (B2R) (BK-2 receptor)

Human Gene Id：624

Human Swiss Prot No：P30411

Mouse Swiss Prot No：P32299

Rat Swiss Prot No：P25023

Immunogen：Synthesized peptide derived from human protein . at AA range: 140-220

Specificity：BKRB2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：43kD

Background： This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. [provided by RefSeq, Jul 2008],

Function：function:Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,online information:Bradykinin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Ubiquitous. Widespread in normal smooth muscle tissue and neurons.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Ubiquitous. Widespread in normal smooth muscle tissue and neurons.