Target：SENP8

Gene Name：SENP8

Protein Name：Sentrin-specific protease 8

Human Gene Id：123228

Human Swiss Prot No：Q96LD8

Mouse Gene Id：71599

Mouse Swiss Prot No：Q9D2Z4

Rat Gene Id：315723

Rat Swiss Prot No：Q5FVJ8

Immunogen：The antiserum was produced against synthesized peptide derived from human SENP8. AA range:161-210

Specificity：SENP8 Polyclonal Antibody detects endogenous levels of SENP8 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SENP8;DEN1;NEDP1;PRSC2;FKSG8;Sentrin-specific protease 8;Deneddylase-1;NEDD8-specific protease 1;Protease; cysteine 2;Sentrin/SUMO-specific protease SENP8

Observed Band(KD)：27kD

Background： This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],

Function：function:Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.,similarity:Belongs to the peptidase C48 family.,tissue specificity:Broadly expressed, with highest levels in kidney and pancreas.,

Expression：Broadly expressed, with highest levels in kidney and pancreas.