Target：SEP10

Gene Name：42988

Protein Name：Septin-10

Human Gene Id：151011

Human Swiss Prot No：Q9P0V9

Mouse Swiss Prot No：Q8C650

Rat Swiss Prot No：Q5PQK1

Immunogen：Synthesized peptide derived from human protein . at AA range: 90-170

Specificity：SEP10 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：49kD

Background： This gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. A pseudogene for this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012],

Function：function:Involved in cytokinesis (Potential). Can bind to GTP and exert GTPase activity.,similarity:Belongs to the septin family.,tissue specificity:Ubiquitous. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines.,

Subcellular Location：Cytoplasm . Cytoplasm, cytoskeleton . Using a GFP-fusion protein, detected in the nucleus. .

Expression：Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines.