Target：SENP7

Gene Name：SENP7

Protein Name：Sentrin-specific protease 7

Human Gene Id：57337

Human Swiss Prot No：Q9BQF6

Mouse Gene Id：66315

Mouse Swiss Prot No：Q8BUH8

Immunogen：The antiserum was produced against synthesized peptide derived from human SENP7. AA range:991-1040

Specificity：SENP7 Polyclonal Antibody detects endogenous levels of SENP7 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SENP7;KIAA1707;SSP2;SUSP2;Sentrin-specific protease 7;SUMO-1-specific protease 2;Sentrin/SUMO-specific protease SENP7

Observed Band(KD)：112kD

Background： The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009],

Function：alternative products:Experimental confirmation may be lacking for some isoforms,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms.,similarity:Belongs to the peptidase C48 family.,

Subcellular Location：Cytoplasm .

Expression： Brain,Epithelium,Fetal kidney,Placenta,