Target：Helios

Gene Name：IKZF2

Protein Name：Zinc finger protein Helios

Human Gene Id：22807

Human Swiss Prot No：Q9UKS7

Mouse Gene Id：22779

Mouse Swiss Prot No：P81183

Immunogen：The antiserum was produced against synthesized peptide derived from human IKZF2. AA range:331-380

Specificity：Helios Polyclonal Antibody detects endogenous levels of Helios protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：IKZF2;HELIOS;ZNFN1A2;Zinc finger protein Helios;Ikaros family zinc finger protein 2

Observed Band(KD)：56kD

Background： This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008],

Function：function:Associates with Ikaros at centromeric heterochromatin.,similarity:Belongs to the Ikaros C2H2-type zinc-finger protein family.,similarity:Contains 6 C2H2-type zinc fingers.,subunit:Interacts with IKZF4 AND IKZF5.,

Subcellular Location：Nucleus .

Expression： Epithelium,Testis,