Target：HDC

Fields：Histidine metabolism;Metabolic pathways

Gene Name：HDC

Protein Name：Histidine decarboxylase

Human Gene Id：3067

Human Swiss Prot No：P19113

Mouse Gene Id：15186

Mouse Swiss Prot No：P23738

Rat Swiss Prot No：P16453

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human HDC. AA range:201-250

Specificity：HDC Polyclonal Antibody detects endogenous levels of HDC protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HDC;Histidine decarboxylase;HDC

Observed Band(KD)：72kD

Background： This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010],

Function：catalytic activity:L-histidine = histamine + CO(2).,cofactor:Pyridoxal phosphate.,pathway:Amine and polyamine biosynthesis; histamine biosynthesis; histamine from L-histidine: step 1/1.,similarity:Belongs to the group II decarboxylase family.,subunit:Homodimer.,

Subcellular Location：cytosol,

Expression： Leukemia,