Target：Granzyme K

Gene Name：GZMK

Protein Name：Granzyme K

Human Gene Id：3003

Human Swiss Prot No：P49863

Mouse Gene Id：14945

Mouse Swiss Prot No：O35205

Rat Gene Id：29165

Rat Swiss Prot No：P49864

Immunogen：The antiserum was produced against synthesized peptide derived from human GRAK. AA range:61-110

Specificity：Granzyme K Polyclonal Antibody detects endogenous levels of Granzyme K protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GZMK;TRYP2;Granzyme K;Fragmentin-3;Granzyme-3;NK-tryptase-2;NK-Tryp-2

Observed Band(KD)：33kD

Background： This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008],

Function：similarity:Belongs to the peptidase S1 family. Granzyme subfamily.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Expressed in lung, spleen, thymus and peripheral blood leukocytes.,

Subcellular Location：Secreted. Cytoplasmic granule.

Expression：Expressed in lung, spleen, thymus and peripheral blood leukocytes.