Target：GPR100

Fields：Neuroactive ligand-receptor interaction;Relaxin signaling pathway

Gene Name：RXFP4

Protein Name：Relaxin-3 receptor 2

Human Gene Id：339403

Human Swiss Prot No：Q8TDU9

Mouse Swiss Prot No：Q7TQP4

Immunogen：The antiserum was produced against synthesized peptide derived from human GPR100. AA range:321-370

Specificity：GPR100 Polyclonal Antibody detects endogenous levels of GPR100 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RXFP4;GPR100;RLN3R2;Relaxin-3 receptor 2;RLN3 receptor 2;G-protein coupled receptor 100;G-protein coupled receptor GPCR142;Insulin-like peptide INSL5 receptor;Relaxin family peptide receptor 4

Observed Band(KD)：38kD

Background： GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008],

Function：function:Receptor for relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in a broader range of tissues including brain, kidney, testis, thymus, placenta, prostate, salivary gland, thyroid and colon.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Expressed in a broader range of tissues including brain, kidney, testis, thymus, placenta, prostate, salivary gland, thyroid and colon.