Target：GPR10

Fields：Neuroactive ligand-receptor interaction

Gene Name：PRLHR

Protein Name：Prolactin-releasing peptide receptor

Human Gene Id：2834

Human Swiss Prot No：P49683

Mouse Gene Id：226278

Mouse Swiss Prot No：Q6VMN6

Rat Gene Id：246075

Rat Swiss Prot No：Q64121

Immunogen：The antiserum was produced against synthesized peptide derived from human PRLHR. AA range:184-233

Specificity：GPR10 Polyclonal Antibody detects endogenous levels of GPR10 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PRLHR;GPR10;GR3;Prolactin-releasing peptide receptor;PrRP receptor;PrRPR;G-protein coupled receptor 10;hGR3

Observed Band(KD)：41kD

Background： PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).[supplied by OMIM, Mar 2008],

Function：function:Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing.,induction:Repressed by bromocriptine, a dopamine agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts through its C-terminal region with the PDZ domain-containing proteins GRIP1, GRIP2 and PICK1. Interacts with PDZ domains 4 and 5 of GRIP1 and with the PDZ domain of PICK1.,tissue specificity:Only detected in the pituitary gland and in all cell types of pituitary adenomas.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Only detected in the pituitary gland and in all cell types of pituitary adenomas.