Target：BOP1

Gene Name：BOP1 KIAA0124

Protein Name：Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein)

Human Gene Id：23246

Human Swiss Prot No：Q14137

Mouse Swiss Prot No：P97452

Rat Swiss Prot No：Q562C2

Immunogen：Synthesized peptide derived from human protein . at AA range: 110-190

Specificity：BOP1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：82kD

Background：function:Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.,induction:By MYC.,similarity:Belongs to the WD repeat BOP1/ERB1 family.,similarity:Contains 7 WD repeats.,subunit:Component of the PeBoW complex, composed of bop1, pes1 and wdr12. Within the PeBoW complex bop1 interacts directly with pes1 and wdr12. The PeBoW complex also associates with the 66S pre-ribosome.,

Function：function:Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.,induction:By MYC.,similarity:Belongs to the WD repeat BOP1/ERB1 family.,similarity:Contains 7 WD repeats.,subunit:Component of the PeBoW complex, composed of bop1, pes1 and wdr12. Within the PeBoW complex bop1 interacts directly with pes1 and wdr12. The PeBoW complex also associates with the 66S pre-ribosome.,

Subcellular Location：Nucleus, nucleolus . Nucleus, nucleoplasm .

Expression： Bone marrow,Brain,Epithelium,Eye,Liver,Lymph,Muscle,Pancreas,