Target:GNA12
Fields:MAPK signaling pathway;cGMP-PKG signaling pathway;Sphingolipid signaling pathway;Phospholipase D signaling pathway;Vascular smooth muscle contraction;Long-term depression;Regulation of actin cytoskeleton;Parathyroid hormone synthesis, secretion and action;Pathogenic Escherichia coli infection;Human cytomegalovirus infection;Pathways in cancer
Gene Name:GNA12
Protein Name:Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12)
Human Gene Id:2768
Human Swiss Prot No:Q03113
Mouse Swiss Prot No:P27600
Rat Swiss Prot No:Q63210
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:GNA12 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):41kD
Background:function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(12) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5.,
Function:function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(12) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5.,
Subcellular Location:Cell membrane ; Lipid-anchor . Lateral cell membrane ; Lipid-anchor . Cytoplasm . CDH1 enhances cell membrane localization. .
Expression: Brain,Pancreas,Placenta,Uterus,