Target：CALRL

Fields：Neuroactive ligand-receptor interaction;Vascular smooth muscle contraction

Gene Name：CALCRL CGRPR

Protein Name：Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor)

Human Gene Id：10203

Human Swiss Prot No：Q16602

Mouse Swiss Prot No：Q9R1W5

Rat Swiss Prot No：Q63118

Immunogen：Synthesized peptide derived from human protein . at AA range: 40-120

Specificity：CALRL Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：50kD

Background：function:Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 2 family.,subunit:Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.,tissue specificity:Predominantly expressed in the lung and heart.,

Function：function:Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 2 family.,subunit:Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.,tissue specificity:Predominantly expressed in the lung and heart.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein.

Expression：Predominantly expressed in the lung and heart.