Target:Calretinin
Gene Name:CALB2
Protein Name:calbindin 2
Human Gene Id:794
Human Swiss Prot No:P22676
Mouse Gene Id:12308
Mouse Swiss Prot No:Q08331
Rat Swiss Prot No:P47728
Immunogen:Synthesized peptide derived from calbindin 2 at AA range: 191-240
Specificity:Calretinin Polyclonal Antibody detects endogenous levels of calbindin 2
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:Calretinin (CR;29 kDa calbindin)
Observed Band(KD):32kD
Background: This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],
Function:function:Calretinin is a calcium-binding protein which is abundant in auditory neurons.,online information:Calbindin entry,similarity:Belongs to the calbindin family.,similarity:Contains 6 EF-hand domains.,tissue specificity:Brain.,
Subcellular Location:nucleus,cytoplasm,cytosol,gap junction,neuron projection,terminal bouton,synapse,
Expression:Brain.