Target:Cadherin-7
Gene Name:CDH7
Protein Name:Cadherin-7
Human Gene Id:1005
Human Swiss Prot No:Q9ULB5
Mouse Gene Id:241201
Mouse Swiss Prot No:Q8BM92
Rat Gene Id:29162
Rat Swiss Prot No:Q5DWV2
Immunogen:The antiserum was produced against synthesized peptide derived from human CDH7. AA range:651-700
Specificity:Cadherin-7 Polyclonal Antibody detects endogenous levels of Cadherin-7 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CDH7;CDH7L1;Cadherin-7
Observed Band(KD):87kD
Background: This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in this gene may be associated with bipolar disease in human patients. This gene is present in a gene cluster on chromosome 18. [provided by RefSeq, May 2016],
Function:function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,
Subcellular Location:Cell membrane; Single-pass type I membrane protein.
Expression: Brain,