Target：Calpain 12

Gene Name：CAPN12

Protein Name：Calpain-12

Human Gene Id：147968

Human Swiss Prot No：Q6ZSI9

Mouse Swiss Prot No：Q9ER56

Immunogen：The antiserum was produced against synthesized peptide derived from human CAPN12. AA range:221-270

Specificity：Calpain 12 Polyclonal Antibody detects endogenous levels of Calpain 12 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CAPN12;Calpain-12;Calcium-activated neutral proteinase 12;CANP 12

Observed Band(KD)：80kD

Background： The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012],

Function：catalytic activity:Broad endopeptidase specificity.,function:Calcium-regulated non-lysosomal thiol-protease.,similarity:Belongs to the peptidase C2 family.,similarity:Contains 1 calpain catalytic domain.,similarity:Contains 1 EF-hand domain.,

Subcellular Location：intracellular,cytoplasm,

Expression： Thalamus,