Target：BECP1

Fields：Autophagy - other;Mitophagy - animal;Autophagy - animal;Apoptosis - multiple species;Apelin signaling pathway;Alzheimer disease;Amyotrophic lateral sclerosis;Huntington disease;Spinocerebellar ataxia;Pathways of neurodegeneration - multiple diseases;Shigellosis;Kaposi sarcoma-associated herpesvirus infection

Gene Name：BECN1P1

Protein Name：Putative beclin-1-like protein (Beclin-1 autophagy-related pseudogene 1)

Human Swiss Prot No：A8MW95

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：BECP1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：47kD

Background：BECN2 (Beclin 2) is a Protein Coding gene. Among its related pathways are Autophagy Pathway and Kaposi's sarcoma-associated herpesvirus infection. An important paralog of this gene is BECN1. Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1.

Subcellular Location：Cytoplasm .

Expression：Present in fetal and adult brain (at protein level).