Target:BD1L1
Gene Name:BOD1L1 BOD1L FAM44A KIAA1327
Protein Name:Biorientation of chromosomes in cell division protein 1-like 1 (Protein FAM44A)
Human Gene Id:259282
Human Swiss Prot No:Q8NFC6
Immunogen:Synthesized peptide derived from human protein . at AA range: 1280-1360
Specificity:BD1L1 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:50-300. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):335kD
Background:Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM.
Subcellular Location:Chromosome . Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection. .