Target：Megsin

Gene Name：SERPINB7

Protein Name：Serpin B7

Human Gene Id：8710

Human Swiss Prot No：O75635

Mouse Swiss Prot No：Q9D695

Immunogen：The antiserum was produced against synthesized peptide derived from human SERPINB7. AA range:111-160

Specificity：Megsin Polyclonal Antibody detects endogenous levels of Megsin protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SERPINB7;Serpin B7;Megsin;TP55

Observed Band(KD)：43kD

Background： This gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],

Function：function:Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Predominantly expressed in mesangial cells.,

Subcellular Location：Cytoplasm .

Expression：Predominantly expressed in mesangial cells. Expressed in the epidermis of the whole body.