Target:POLDIP3
Gene Name:POLDIP3
Protein Name:Polymerase delta-interacting protein 3
Human Gene Id:84271
Human Swiss Prot No:Q9BY77
Mouse Swiss Prot No:Q8BG81
Immunogen:The antiserum was produced against synthesized peptide derived from human POLDIP3. AA range:348-397
Specificity:POLDIP3 Polyclonal Antibody detects endogenous levels of POLDIP3 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:POLDIP3;KIAA1649;PDIP46;Polymerase delta-interacting protein 3;46 kDa DNA polymerase delta interaction protein;p46;S6K1 Aly/REF-like target;SKAR
Observed Band(KD):46kD
Background: This gene encodes an RRM (RNA recognition motif)-containing protein that participates in the regulation of translation by recruiting ribosomal protein S6 kinase beta-1 to mRNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Function:PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Interacts with POLD2.,
Subcellular Location:Nucleus. Nucleus speckle. Cytoplasm. Nucleocytoplasmic shuttling protein.
Expression: Brain,Epithelium,Ovarian carcinoma,Placenta,Skin,Testis,