Target：BAI-3

Gene Name：BAI3

Protein Name：Brain-specific angiogenesis inhibitor 3

Human Gene Id：577

Human Swiss Prot No：O60242

Mouse Gene Id：210933

Mouse Swiss Prot No：Q80ZF8

Immunogen：The antiserum was produced against synthesized peptide derived from human BAI3. AA range:211-260

Specificity：BAI-3 Polyclonal Antibody detects endogenous levels of BAI-3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：BAI3;KIAA0550;Brain-specific angiogenesis inhibitor 3

Molecular Weight(Da)：171kD

Background： This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008],

Function：function:Might be involved in angiogenesis inhibition and suppression of glioblastoma.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 CUB domain.,similarity:Contains 1 GPS domain.,similarity:Contains 4 TSP type-1 domains.,tissue specificity:Strongly expressed in brain. Also detected in heart. Reduced expression is observed in some glioblastoma cell lines.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein .

Expression：Strongly expressed in brain. Also detected in heart. Reduced expression in some glioblastoma cell lines.