Target:ARP-1
Gene Name:NR2F2
Protein Name:COUP transcription factor 2
Human Gene Id:7026
Human Swiss Prot No:P24468
Mouse Gene Id:11819
Mouse Swiss Prot No:P43135
Rat Gene Id:113984
Rat Swiss Prot No:O09018
Immunogen:The antiserum was produced against synthesized peptide derived from human COT2. AA range:1-50
Specificity:ARP-1 Polyclonal Antibody detects endogenous levels of ARP-1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NR2F2;ARP1;TFCOUP2;COUP transcription factor 2;COUP-TF2;Apolipoprotein A-I regulatory protein 1;ARP-1;COUP transcription factor II;COUP-TF II;Nuclear receptor subfamily 2 group F member 2
Observed Band(KD):45kD
Background: This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010],
Function:function:Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR2 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Interacts with SQSTM1 (By similarity). Binds DNA as a homodimer.,tissue specificity:Found in all tissues.,
Subcellular Location:Nucleus.
Expression:Ubiquitous. Expressed in the stromal cells of developing fetal ovaries (PubMed:29478779).