Target：EIF5

Gene Name：EIF5

Protein Name：Eukaryotic translation initiation factor 5

Human Gene Id：1983

Human Swiss Prot No：P55010

Mouse Gene Id：1.00048e+008

Mouse Swiss Prot No：P59325

Rat Gene Id：56783

Rat Swiss Prot No：Q07205

Immunogen：Synthesized peptide derived from the Internal region of human eIF5.

Specificity：eIF5 Polyclonal Antibody detects endogenous levels of eIF5 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：EIF5;Eukaryotic translation initiation factor 5;eIF-5

Molecular Weight(Da)：49kD

Background： Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010],

Function：function:Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).,similarity:Belongs to the eIF-2-beta/eIF-5 family.,similarity:Contains 1 W2 domain.,

Subcellular Location：nucleus,cytoplasm,cytosol,plasma membrane,cell-cell adherens junction,

Expression： Brain,Epithelium,Lymph,Pooled,Uterus,