Target：EFNB2
Fields：Axon guidance
Gene Name：EFNB2 EPLG5 HTKL LERK5
Protein Name：Ephrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L)
Human Gene Id：1948
Human Swiss Prot No：P52799
Mouse Swiss Prot No：P52800
Immunogen：Synthesized peptide derived from human protein . at AA range: 210-290
Specificity：EFNB2 Polyclonal Antibody detects endogenous levels of protein.
Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000 ELISA 1:5000-20000
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD)：36kD
Background： This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008],
Function：function:Binds to the receptor tyrosine kinases EPHB4 and EPHA3. May play a role in constraining the orientation of longitudinally projecting axons.,PTM:Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.,similarity:Belongs to the ephrin family.,subunit:Interacts with PDZRN3 (By similarity). Binds to the receptor tyrosine kinases EPHB4 and EPHA3. Binds to Nipah virus G protein.,tissue specificity:Lung and kidney.,
Subcellular Location：Cell membrane ; Single-pass type I membrane protein . Cell junction, adherens junction .
Expression：Lung and kidney.
