Target：DNA Pol μ

Fields：Non-homologous end-joining

Gene Name：POLM

Protein Name：DNA-directed DNA/RNA polymerase mu

Human Gene Id：27434

Human Swiss Prot No：Q9NP87

Mouse Swiss Prot No：Q9JIW4

Immunogen：Synthesized peptide derived from DNA Pol μ . at AA range: 210-290

Specificity：DNA Pol μ Polyclonal Antibody detects endogenous levels of DNA Pol μ protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：POLM;polmu;DNA-directed DNA/RNA polymerase mu;Pol Mu;Terminal transferase

Observed Band(KD)：54kD

Background：catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,

Function：catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,

Subcellular Location：Nucleus .

Expression：Expressed in a number of tissues. Abundant in thymus.