Target：CYP26C1

Fields：Retinol metabolism;Metabolic pathways

Gene Name：CYP26C1

Protein Name：Cytochrome P450 26C1

Human Gene Id：340665

Human Swiss Prot No：Q6V0L0

Immunogen：Synthesized peptide derived from the Internal region of human CYP26C1.

Specificity：CYP26C1 Polyclonal Antibody detects endogenous levels of CYP26C1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CYP26C1;Cytochrome P450 26C1

Observed Band(KD)：60kD

Background：cytochrome P450 family 26 subfamily C member 1(CYP26C1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid, and thus contributes to the regulation of retinoic acid levels in cells and tissues. This gene is adjacent to a related gene on chromosome 10q23.33. [provided by RefSeq, Jul 2008],

Function：cofactor:Heme group.,function:Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).,induction:By retinoic acid.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Detected in most tissues at very low level.,

Subcellular Location：Membrane ; Single-pass membrane protein .

Expression：Detected in most tissues at very low level.