Target：GBDR1

Gene Name：UBAC1

Protein Name：Ubiquitin-associated domain-containing protein 1

Human Gene Id：10422

Human Swiss Prot No：Q9BSL1

Mouse Swiss Prot No：Q8VDI7

Immunogen：The antiserum was produced against synthesized peptide derived from human UBAC1. AA range:91-140

Specificity：GBDR1 Polyclonal Antibody detects endogenous levels of GBDR1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：UBAC1;GBDR1;KPC2;UBADC1;Ubiquitin-associated domain-containing protein 1;UBA domain-containing protein 1;E3 ubiquitin-protein ligase subunit KPC2;Glialblastoma cell differentiation-related protein 1;Kip1 ubiquitination-promoting com

Observed Band(KD)：45kD

Background：function:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 STI1 domain.,similarity:Contains 1 ubiquitin-like domain.,similarity:Contains 2 UBA domains.,subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain.,tissue specificity:Ubiquitous.,

Function：function:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 STI1 domain.,similarity:Contains 1 ubiquitin-like domain.,similarity:Contains 2 UBA domains.,subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain.,tissue specificity:Ubiquitous.,

Subcellular Location：Cytoplasm .

Expression：Ubiquitous.