Target：FN3K

Gene Name：FN3K

Protein Name：Fructosamine-3-kinase (EC 2.7.1.-)

Human Gene Id：64122

Human Swiss Prot No：Q9H479

Mouse Swiss Prot No：Q9ER35

Immunogen：Synthesized peptide derived from human protein . at AA range: 130-210

Specificity：FN3K Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：33kD

Background： A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012],

Function：function:May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme.,similarity:Belongs to the fructosamine kinase family.,subunit:Monomer.,tissue specificity:Expressed in erythrocytes.,

Subcellular Location：cytosol,

Expression：Widely expressed (PubMed:11522682). Expressed in erythrocytes (PubMed:11016445).