Target:IMP1L
Fields:Protein export
Gene Name:IMMP1L
Protein Name:Mitochondrial inner membrane protease subunit 1 (EC 3.4.21.-) (IMP1-like protein)
Human Gene Id:196294
Human Swiss Prot No:Q96LU5
Mouse Swiss Prot No:Q9CQU8
Immunogen:Synthesized peptide derived from human protein . at AA range: 70-150
Specificity:IMP1L Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):18kD
Background: The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 and IMP2 (IMMP2L; MIM 605977) are the catalytic subunits of the IMP complex (Burri et al., 2005 [PubMed 15814844]).[supplied by OMIM, Sep 2008],
Function:function:Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.,similarity:Belongs to the peptidase S26 family. IMP1 subfamily.,subunit:Heterodimer of 2 subunits, IMMPL1 and IMMPL2.,
Subcellular Location:Mitochondrion inner membrane .
Expression: Cerebellum,Eye,