Target：NMB

Fields：Neuroactive ligand-receptor interaction

Gene Name：NMB

Protein Name：Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]

Human Gene Id：4828

Human Swiss Prot No：P08949

Mouse Swiss Prot No：Q9CR53

Immunogen：Synthesized peptide derived from human protein . at AA range: 20-100

Specificity：NMB Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：13kD

Background： This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015],

Function：function:Stimulates smooth muscle contraction in a manner similar to that of bombesin.,similarity:Belongs to the bombesin/neuromedin-B/ranatensin family.,

Subcellular Location：Secreted . Cell projection, neuron projection . In neurons of the retrotrapezoid nucleus//parafacial respiratory group, expressed on neuron projections which project into the pre-Botzinger complex. .

Expression： Brain,Hypothalamus,Ovary,