Target：Neurocalcin δ
Fields：Olfactory transduction
Gene Name：NCALD
Protein Name：Neurocalcin-delta
Human Gene Id：83988
Human Swiss Prot No：P61601
Mouse Gene Id：52589
Mouse Swiss Prot No：Q91X97
Rat Gene Id：553106
Rat Swiss Prot No：Q5PQN0
Immunogen：Synthesized peptide derived from Neurocalcin δ . at AA range: 370-450
Specificity：Neurocalcin δ Polyclonal Antibody detects endogenous levels of Neurocalcin δ protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：NCALD;Neurocalcin-delta
Molecular Weight(Da)：22kD
Background： This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
Function：function:May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.,similarity:Belongs to the recoverin family.,similarity:Contains 4 EF-hand domains.,tissue specificity:Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine.,
Subcellular Location：intracellular,cytosol,clathrin coat of trans-Golgi network vesicle,extracellular exosome,
Expression：Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine.
