Target:Neurocan
Gene Name:NCAN
Protein Name:Neurocan core protein
Human Gene Id:1463
Human Swiss Prot No:O14594
Mouse Swiss Prot No:P55066
Immunogen:Synthesized peptide derived from Neurocan . at AA range: 370-450
Specificity:Neurocan Polyclonal Antibody detects endogenous levels of Neurocan protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NCAN;CSPG3;NEUR;Neurocan core protein;Chondroitin sulfate proteoglycan 3
Observed Band(KD):145kD
Background: Neurocan is a chondroitin sulfate proteoglycan thought to be involved in the modulation of cell adhesion and migration.[supplied by OMIM, Jul 2002],
Function:function:May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid.,online information:Neurocan,similarity:Belongs to the aggrecan/versican proteoglycan family.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,similarity:Contains 2 EGF-like domains.,similarity:Contains 2 Link domains.,tissue specificity:Brain.,
Subcellular Location:Secreted .
Expression:Brain.