Target:Neuro D2
Gene Name:NEUROD2
Protein Name:Neurogenic differentiation factor 2
Human Gene Id:4761
Human Swiss Prot No:Q15784
Mouse Gene Id:18013
Mouse Swiss Prot No:Q62414
Rat Gene Id:54276
Rat Swiss Prot No:Q63689
Immunogen:The antiserum was produced against synthesized peptide derived from human NDF2. AA range:61-110
Specificity:Neuro D2 Polyclonal Antibody detects endogenous levels of Neuro D2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NEUROD2;BHLHA1;NDRF;Neurogenic differentiation factor 2;NeuroD2;Class A basic helix-loop-helix protein 1;bHLHa1;NeuroD-related factor;NDRF
Observed Band(KD):48kD
Background: This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates. [provided by RefSeq, Jul 2008],
Function:function:Appears to mediate neuronal differentiation.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,
Subcellular Location:Nucleus .
Expression: Brain,