Target:NDUFA9
Fields:Oxidative phosphorylation;Metabolic pathways;Thermogenesis;Retrograde endocannabinoid signaling;Non-alcoholic fatty liver disease;Alzheimer disease;Parkinson disease;Amyotrophic lateral sclerosis;Huntington disease;Prion disease;Pathways of neurodegeneration - multiple diseases;Chemical carcinogenesis - reactive oxygen species;Diabetic cardiomyopathy
Gene Name:NDUFA9
Protein Name:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9 mitochondrial
Human Gene Id:4704
Human Swiss Prot No:Q16795
Mouse Gene Id:66108
Mouse Swiss Prot No:Q9DC69
Rat Gene Id:362440
Rat Swiss Prot No:Q5BK63
Immunogen:The antiserum was produced against synthesized peptide derived from human NDUFA9. AA range:87-136
Specificity:NDUFA9 Polyclonal Antibody detects endogenous levels of NDUFA9 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NDUFA9;NDUFS2L;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9; mitochondrial;Complex I-39kD;CI-39kD;NADH-ubiquinone oxidoreductase 39 kDa subunit
Observed Band(KD):40kD
Background: The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. A pseudogene has been identified on chromosome 12. [provided by RefSeq, May 2010],
Function:cofactor:Binds 1 FAD per subunit.,function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFA9 subunit family.,subunit:Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.,
Subcellular Location:Mitochondrion matrix .
Expression: Blood,Colon,Liver,Muscle,Placenta,Skeletal muscle,