Target：NT-4

Fields：MAPK signaling pathway;Ras signaling pathway;PI3K-Akt signaling pathway;Neurotrophin signaling pathway

Gene Name：NTF4

Protein Name：Neurotrophin-4

Human Gene Id：4909

Human Swiss Prot No：P34130

Mouse Gene Id：78405

Mouse Swiss Prot No：Q80VU4

Rat Gene Id：25730

Rat Swiss Prot No：P34131

Immunogen：The antiserum was produced against synthesized peptide derived from human NT-4. AA range:71-120

Specificity：NT-4 Polyclonal Antibody detects endogenous levels of NT-4 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NTF4;NTF5;Neurotrophin-4;NT-4;Neurotrophin-5;NT-5;Neutrophic factor 4

Molecular Weight(Da)：22kD

Background： This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq, Jul 2008],

Function：function:Target-derived survival factor for peripheral sensory sympathetic neurons.,similarity:Belongs to the NGF-beta family.,tissue specificity:Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.,

Subcellular Location：Secreted.

Expression：Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.