Target:NTF2
Gene Name:NUTF2
Protein Name:Nuclear transport factor 2
Human Gene Id:10204
Human Swiss Prot No:P61970
Mouse Gene Id:621832
Mouse Swiss Prot No:P61971
Rat Gene Id:291981
Rat Swiss Prot No:P61972
Immunogen:The antiserum was produced against synthesized peptide derived from human NUTF2. AA range:67-116
Specificity:NTF2 Polyclonal Antibody detects endogenous levels of NTF2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NUTF2;NTF2;Nuclear transport factor 2;NTF-2;Placental protein 15;PP15
Observed Band(KD):15kD
Background: This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62. [provided by RefSeq, Apr 2016],
Function:function:Facilitates protein transport into the nucleus. Interacts with the nucleoporin p62 and with Ran. Acts at a relatively late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import.,similarity:Contains 1 NTF2 domain.,subunit:Homodimer.,
Subcellular Location:Cytoplasm, cytosol . Nucleus outer membrane . Nucleus, nuclear pore complex . Nucleus inner membrane . Nucleus, nucleoplasm . At steady state it is essentially nucleoplasmic, enriched in nucleoplasmic foci. .
Expression: Lung,