Target：PITSLRE

Gene Name：CDK11B

Protein Name：Cyclin-dependent kinase 11B

Human Gene Id：984

Human Swiss Prot No：P21127

Mouse Gene Id：12537

Mouse Swiss Prot No：P24788

Immunogen：The antiserum was produced against synthesized peptide derived from human CDC2L1. AA range:10-59

Specificity：PITSLRE Polyclonal Antibody detects endogenous levels of PITSLRE protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CDK11B;CDC2L1;CDK11;PITSLREA;PK58;Cyclin-dependent kinase 11B;Cell division cycle 2-like protein kinase 1;CLK-1;Cell division protein kinase 11B;Galactosyltransferase-associated protein kinase p58/GTA;PITSLRE serine/threonine-prot

Observed Band(KD)：92kD

Background： This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],

Function：caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,

Subcellular Location：Cytoplasm. Nucleus.

Expression：Expressed ubiquitously. Some evidence of isoform-specific tissue distribution.