Target:PITPβ
Gene Name:PITPNB
Protein Name:Phosphatidylinositol transfer protein beta isoform
Human Gene Id:23760
Human Swiss Prot No:P48739
Mouse Gene Id:56305
Mouse Swiss Prot No:P53811
Rat Gene Id:114561
Rat Swiss Prot No:P53812
Immunogen:The antiserum was produced against synthesized peptide derived from human PITPNB. AA range:20-69
Specificity:PITPβ Polyclonal Antibody detects endogenous levels of PITPβ protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:PITPNB;Phosphatidylinositol transfer protein beta isoform;PI-TP-beta;PtdIns transfer protein beta;PtdInsTP beta
Observed Band(KD):32kD
Background: This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013],
Function:function:Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.,PTM:Constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity but is required for Golgi targeting.,similarity:Belongs to the PtdIns transfer protein family. Class I subfamily.,tissue specificity:Widely expressed in various tissues including brain.,
Subcellular Location:Golgi apparatus . Golgi apparatus membrane . Endoplasmic reticulum membrane .
Expression:Widely expressed in various tissues including brain.