Target：Rab 5C

Fields：Ras signaling pathway;Endocytosis;Phagosome;Vasopressin-regulated water reabsorption;Salmonella infection;Amoebiasis;Tuberculosis

Gene Name：RAB5C

Protein Name：Ras-related protein Rab-5C

Human Gene Id：5878

Human Swiss Prot No：P51148

Mouse Gene Id：19345

Mouse Swiss Prot No：P35278

Immunogen：The antiserum was produced against synthesized peptide derived from human RAB5C. AA range:122-171

Specificity：Rab 5C Polyclonal Antibody detects endogenous levels of Rab 5C protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RAB5C;RABL;Ras-related protein Rab-5C;L1880;RAB5L

Observed Band(KD)：30kD

Background： Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010],

Function：function:Protein transport. Probably involved in vesicular traffic.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Binds EEA1.,

Subcellular Location：Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome membrane ; Lipid-anchor . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .

Expression： Brain,Lung,