Target：Syndecan-4
Fields：ECM-receptor interaction;Cell adhesion molecules;Proteoglycans in cancer;Fluid shear stress and atherosclerosis
Gene Name：SDC4
Protein Name：Syndecan-4
Human Gene Id：6385
Human Swiss Prot No：P31431
Mouse Gene Id：20971
Mouse Swiss Prot No：O35988
Rat Gene Id：24771
Rat Swiss Prot No：P34901
Immunogen：The antiserum was produced against synthesized peptide derived from human Syndecan4 around the phosphorylation site of Ser179. AA range:145-194
Specificity：Phospho-Syndecan-4 (S179) Polyclonal Antibody detects endogenous levels of Syndecan-4 protein only when phosphorylated at S179.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：SDC4;Syndecan-4;SYND4;Amphiglycan;Ryudocan core protein
Molecular Weight(Da)：22kD
Background： The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008],
Function：function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan.,similarity:Belongs to the syndecan proteoglycan family.,subunit:Homodimer. Interacts with CDCP1, with GIPC PDZ domain and with NUDT16L1/SDOS (By similarity). Interacts with SDCBP.,tissue specificity:Expressed in epithelial and fibroblastic cells.,
Subcellular Location：[Isoform 1]: Membrane ; Single-pass type I membrane protein . Secreted . Shedding of the ectodomain produces a soluble form. .; [Isoform 2]: Secreted.
Expression：Expressed in epithelial and fibroblastic cells.
