Target：SR-1D

Fields：cAMP signaling pathway;Neuroactive ligand-receptor interaction;Serotonergic synapse;Taste transduction

Gene Name：HTR1D

Protein Name：5-hydroxytryptamine receptor 1D

Human Gene Id：3352

Human Swiss Prot No：P28221

Mouse Gene Id：15552

Mouse Swiss Prot No：Q61224

Rat Gene Id：25323

Rat Swiss Prot No：P28565

Immunogen：Synthesized peptide derived from SR-1D . at AA range: 120-200

Specificity：SR-1D Polyclonal Antibody detects endogenous levels of SR-1D protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HTR1D;HTR1DA;HTRL;5-hydroxytryptamine receptor 1D;5-HT-1D;5-HT1D;5-HT-1D-alpha;Serotonin receptor 1D

Observed Band(KD)：41kD

Background：function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Function：function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein .

Expression：Detected in brain neocortex and caudate nucleus (at protein level).