Target：SOX4

Fields：MicroRNAs in cancer

Gene Name：SOX4

Protein Name：Transcription factor SOX-4

Human Gene Id：6659

Human Swiss Prot No：Q06945

Mouse Swiss Prot No：Q06831

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：SOX4 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：52kD

Background：SRY-box 4(SOX4) Homo sapiens This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008],

Function：function:Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Interacts with UBE2I.,tissue specificity:Testis, brain, and heart.,

Subcellular Location：Nucleus .

Expression：Testis, brain, and heart.