Target：SOX3

Gene Name：SOX3

Protein Name：Transcription factor SOX-3

Human Gene Id：6658

Human Swiss Prot No：P41225

Mouse Swiss Prot No：P53784

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：SOX3 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：49kD

Background：SRY-box 3(SOX3) Homo sapiens This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency. [provided by RefSeq, Jul 2008],

Function：caution:Was originally (PubMed:1614875) termed SOX-9.,disease:Defects in SOX3 are a cause of panhypopituitarism X-linked (PHPX) [MIM:312000]. Affected individuals have absent infundibulum, anterior pituitary hypoplasia, and ectopic posterior pituitary.,disease:Defects in SOX3 are the cause of mental retardation X-linked with isolated growth hormone deficiency (MRXGH) [MIM:300123].,similarity:Contains 1 HMG box DNA-binding domain.,

Subcellular Location：Nucleus.

Expression： Brain,Spinal cord,