Target：SNRK

Gene Name：SNRK KIAA0096 SNFRK

Protein Name：SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)

Human Gene Id：54861

Human Swiss Prot No：Q9NRH2

Mouse Swiss Prot No：Q8VDU5

Rat Swiss Prot No：Q63553

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：SNRK Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：84kD

Background： SNRK is a member of the sucrose nonfermenting (SNF)-related kinase family of serine/threonine kinases (Kertesz et al., 2002 [PubMed 12234663]).[supplied by OMIM, Apr 2009],

Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-173 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,tissue specificity:Expressed in hematopoietic progenitor cells and leukemic cell lines. Weakly expressed in the testis.,

Subcellular Location：Nucleus .

Expression：Expressed in hematopoietic progenitor cells and leukemic cell lines. Weakly expressed in the testis.