Target:SNPH
Gene Name:SNPH KIAA0374
Protein Name:Syntaphilin
Human Gene Id:9751
Human Swiss Prot No:O15079
Mouse Swiss Prot No:Q80U23
Rat Swiss Prot No:B5DF41
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:SNPH Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):54kD
Background: Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],
Function:function:Inhibits SNARE complex formation by absorbing free syntaxin-1.,similarity:Belongs to the rad21 family.,subunit:Binds to syntaxin-1.,tissue specificity:Brain specific. Found in synapses.,
Subcellular Location:Membrane ; Single-pass membrane protein . Cell junction, synapse, synaptosome.
Expression:Brain specific. Found in synapses.