Target：ACOT12

Fields：Pyruvate metabolism;Metabolic pathways

Gene Name：ACOT12

Protein Name：Acyl-coenzyme A thioesterase 12

Human Gene Id：134526

Human Swiss Prot No：Q8WYK0

Mouse Gene Id：74156

Mouse Swiss Prot No：Q9DBK0

Rat Gene Id：170570

Rat Swiss Prot No：Q99NB7

Immunogen：The antiserum was produced against synthesized peptide derived from human ACOT12. AA range:281-330

Specificity：ACOT12 Polyclonal Antibody detects endogenous levels of ACOT12 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ACOT12;CACH;CACH1;STARD15;Acyl-coenzyme A thioesterase 12;Acyl-CoA thioesterase 12;Acyl-CoA thioester hydrolase 12;Cytoplasmic acetyl-CoA hydrolase 1;CACH-1;hCACH-1;START domain-containing protein 15;StARD15

Molecular Weight(Da)：62kD

Background：catalytic activity:Acetyl-CoA + H(2)O = CoA + acetate.,function:Hydrolyzes acetyl-CoA to acetate and CoA.,pathway:Carbohydrate metabolism; pyruvate metabolism.,similarity:Contains 1 START domain.,similarity:Contains 2 acyl coenzyme A hydrolase domains.,subunit:Homodimer or homotetramer.,

Function：catalytic activity:Acetyl-CoA + H(2)O = CoA + acetate.,function:Hydrolyzes acetyl-CoA to acetate and CoA.,pathway:Carbohydrate metabolism; pyruvate metabolism.,similarity:Contains 1 START domain.,similarity:Contains 2 acyl coenzyme A hydrolase domains.,subunit:Homodimer or homotetramer.,

Subcellular Location：Cytoplasm, cytosol .

Expression： Chondrosarcoma Lung Metastasis,Liver,