Target:ACOT1
Fields:Fatty acid elongation;Biosynthesis of unsaturated fatty acids;Metabolic pathways;Ovarian steroidogenesis
Gene Name:ACOT1
Protein Name:Acyl-coenzyme A thioesterase 1
Human Gene Id:641371
Human Swiss Prot No:Q86TX2
Mouse Swiss Prot No:O55137
Immunogen:The antiserum was produced against synthesized peptide derived from human ACOT1. AA range:91-140
Specificity:ACOT1 Polyclonal Antibody detects endogenous levels of ACOT1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:ACOT1;CTE1;Acyl-coenzyme A thioesterase 1;Acyl-CoA thioesterase 1;CTE-I;CTE-Ib;Inducible cytosolic acyl-coenzyme A thioester hydrolase;Long chain acyl-CoA thioester hydrolase;Long chain acyl-CoA hydrolase
Observed Band(KD):46kD
Background:catalytic activity:Palmitoyl-CoA + H(2)O = CoA + palmitate.,function:Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16.,similarity:Belongs to the C/M/P thioester hydrolase family.,subunit:Monomer.,
Function:catalytic activity:Palmitoyl-CoA + H(2)O = CoA + palmitate.,function:Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16.,similarity:Belongs to the C/M/P thioester hydrolase family.,subunit:Monomer.,
Subcellular Location:Cytoplasm, cytosol .
Expression: Neuroblastoma,