Target：SAPAP1

Fields：Glutamatergic synapse

Gene Name：DLGAP1

Protein Name：Disks large-associated protein 1

Human Gene Id：9229

Human Swiss Prot No：O14490

Mouse Gene Id：224997

Mouse Swiss Prot No：Q9D415

Rat Gene Id：65040

Rat Swiss Prot No：P97836

Immunogen：The antiserum was produced against synthesized peptide derived from human DLGP1. AA range:791-840

Specificity：SAPAP1 Polyclonal Antibody detects endogenous levels of SAPAP1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：DLGAP1;DAP1;GKAP;Disks large-associated protein 1;DAP-1;Guanylate kinase-associated protein;hGKAP;PSD-95/SAP90-binding protein 1;SAP90/PSD-95-associated protein 1;SAPAP1

Observed Band(KD)：108kD

Background：function:Part of the postsynaptic scaffold in neuronal cells.,similarity:Belongs to the SAPAP family.,subcellular location:Found in postsynaptic density of neuronal cells.,subunit:Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1.,tissue specificity:Expressed in brain.,

Function：function:Part of the postsynaptic scaffold in neuronal cells.,similarity:Belongs to the SAPAP family.,subcellular location:Found in postsynaptic density of neuronal cells.,subunit:Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1.,tissue specificity:Expressed in brain.,

Subcellular Location：Cell membrane ; Peripheral membrane protein . Cell junction, synapse, postsynaptic density . Cell junction, synapse .

Expression：Expressed in brain.