Target：AK5

Fields：Purine metabolism;Thiamine metabolism;Metabolic pathways;Nucleotide metabolism;Biosynthesis of cofactors

Gene Name：AK5

Protein Name：Adenylate kinase isoenzyme 5

Human Gene Id：26289

Human Swiss Prot No：Q9Y6K8

Mouse Gene Id：229949

Mouse Swiss Prot No：Q920P5

Immunogen：The antiserum was produced against synthesized peptide derived from human AK5. AA range:391-440

Specificity：AK5 Polyclonal Antibody detects endogenous levels of AK5 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：AK5;Adenylate kinase isoenzyme 5;AK 5;ATP-AMP transphosphorylase 5

Observed Band(KD)：25kD

Background：adenylate kinase 5(AK5) Homo sapiens This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

Function：catalytic activity:ATP + AMP = 2 ADP.,function:Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP.,similarity:Belongs to the adenylate kinase family.,subunit:Monomer.,tissue specificity:Brain specific.,

Subcellular Location：Cytoplasm .

Expression：Brain specific.