Target：AGT2

Fields：Alanine, aspartate and glutamate metabolism;Glycine, serine and threonine metabolism;Cysteine and methionine metabolism;Valine, leucine and isoleucine degradation;Metabolic pathways

Gene Name：AGXT2 AGT2

Protein Name：Alanine--glyoxylate aminotransferase 2, mitochondrial (AGT 2) (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (Beta-ALAAT II) (Beta-alanine-pyruvate aminotransferas

Human Gene Id：64902

Human Swiss Prot No：Q9BYV1

Mouse Swiss Prot No：Q3UEG6

Rat Swiss Prot No：Q64565

Immunogen：Synthesized peptide derived from human protein . at AA range: 340-420

Specificity：AGT2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：56kD

Background： The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in this gene affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],

Function：catalytic activity:(R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine.,catalytic activity:L-alanine + glyoxylate = pyruvate + glycine.,cofactor:Pyridoxal phosphate.,similarity:Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homotetramer.,

Subcellular Location：Mitochondrion .

Expression： Kidney,